| 1. | Some transcriptional factors may be expressed to regulate the expression of other genes to resist to antibiotics
通过一些与转录有关一些因子的表达变化来调节细菌的基因表达。 |
| 2. | But up to now , the relationship beween islet - 1 , a lim homeodomain transcriptional factor , and pituitary development is unclear
到目前为止， lim同源结构域转录因子islet - 1与垂体发育之间的关系尚不清楚。 |
| 3. | Therefore , the osbhlh1 gene is one novel member of the bhlh transcriptional factors family possible involved in the cold signal transduction pathway
表明osbhlh1可能是参与冷胁迫信号传导途径中的一个新的转录因子，转基因耐逆试验正在进行。 |
| 4. | A method of predicting human tumor peculiar promoter is introduced . by using transcriptional factor binding sites , this technique can receive a result well and truly
摘要本文介绍了一种利用转录因子结合位元点应用计算机技术对人类肿瘤特异性启动子进行预测的方法。实验结果证明该方法具有较高的准确性。 |
| 5. | C1 and r are two kinds of transcription factors from maize . cl is one of a myb transcriptional factors , and r , belongs to bhlh family . they can interact with each other and have important functions during anthocyanin synthesis
C1与r是两类从玉米中分离到的转录因子基因， c1属myb转录因子， r属bhlh转录因子，它们之间的协同作用在在花青素合成中起着非常重要的调节作用。 |
| 6. | Gene ( tscoxi ) , structure protein gene ( tsdcn , tsmmip , tsb - actiri ) , transcriptional factor gene ( tshmg1 , tsdap5 ) . the cdna library can be used to provide expressed sequence tags ( ests ) . the stage - specific cdna library will be a useful resource for the study of gene structure , expression and regulatory during the early process of embroygensis of trionyx sinensis
Blast分析表明， 12个序列代表5种类型的基因:核糖体蛋白基因( tsrpl4 ， tsrp丈6 ，招天尸乙26 ) 、组织特异性表达的基因(钻尸乃从招月叨火d ) 、线粒体基因( tsc “叨、结构蛋白基因伽dc从括人从石， ， ts刀一ctin ) 、编码转录因子的基因(招月沏吟1 ， tsda尸5 ) 。 |
| 7. | Studies revealed that p - catenin dissociated from ccc and translocated into free catenin pool in cytosol after it has been phosphorylated at tyrosine or serine residues , and in this situation , the ccc has been disrupted and cell adhesion function disturbed . a large amount of the free p - catenins in the cytosol can be degraded by the tumor suppressor apc , and the remains translocate into nucleus and bind to transcriptional factor tcf / lef in the nucleus and then promote cell proliferation related gene or anti - apoptosis gene transcription
当-连环蛋白酪氨酸或丝氨酸残基磷酸化后，就与ajs发生解离而游离到细胞浆中，此时细胞的粘附功能也发生障碍，游离到胞浆中的-连环蛋白，一部分被抑癌因子apc降解，一部分则转移到细胞核内，与核内的转录因子tcf lef结合，启动与细胞增殖有关的基因转录。 |
| 8. | In order to study the expression of 3 - defensins in liver as acute phase response proteins , a murine systemic acute phase responsive model was established by intraperitoneal injection o f lipopolysaccharide ( lps ) in our study . the mbd3 cdna sequence ( 145 - 169 bp ) was labled with [ - 32p ] atp as a probe to detect mbd3 mrna in different tissues by northern blot and analyze the time - and dose - dependant expression caused by lps . the 5 " flanking sequence ( - 167 - 179 bp ) of the mbd3 gene was designed as the probe and labled with [ - 32p ] dctp to investigate the binding of transcriptional factors to this region by electrophoretic mobility shift assay ( emsa ) and south - western blot
以小鼠mbd3基因145 ? 169bpcdna序列合成探针，经[ - ~ ( 32 ) p ] atp标记后通过northernblot方法检测mbd3在肝脏中的表达，同时分析了mbd3基因诱导表达的组织特异性，剂效和时效关系；结合mbd3基因启动子区序列分析，以- 164 ? - 179bp双链dna序列合成探针，经[ - ~ ( 32 ) p ] dctp标记后通过电泳迁移率改变实验( emsa )和south ? westernblot方法对参与mbd3在肝脏中诱导表达调节的转录因子进行分析。 |
| 9. | These results suggest that the transcriptional factor is the p50 - p65 heterodimer of nf - b . conclusion : 1 . the expression of mbd3 gene can be induced in liver during the systemic acute - phase response to the challenge by lps ; 2 . the acute phase - related mbd3 gene expression appears to be time - and dose - dependant of lps stimulation ; 3
结论: 1 . lps刺激引起小鼠急性时相反应可诱导mbd3基因在肝脏中表达; 2 . lps诱导的mbd3基因的急性时相表达具有剂量和时间依赖性; 3 . nf一‘ b活化后参与mbd3基因诱导表达的转录调节。 |
| 10. | The full - length of leeil2 gene is 1845bp , leeil2 encodes transcriptional factor . in this study , in order to investigate the role of leeil2 in tomato fruit ripening , three expression vectors had been constructed and mobilized into agrobacterium twnefacious eha105
番茄中得到的ein3同源基因为leeil1 2 3 ，其中leeil2与番茄果实成熟衰老过程密切相关，该基因全长1845bp ，可能编码细胞核内转录因子。本研究对leeil2基因进行了转基因分析，为进一步研究leeil2在番茄果实成熟过程中的作用与功能奠定基础。 |
